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Diazepam is N-demethylated by CYP3A4 and 2C19 towards the Lively metabolite N-desmethyldiazepam, and is also hydroxylated by CYP3A4 to the Energetic metabolite temazepam. N-desmethyldiazepam and temazepam are each additional metabolized to oxazepam. Temazepam and oxazepam are largely eliminated by glucuronidation.Oral Valium may be applied adjuncti